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23.08.2019 | Institute BCN

Lipolysis with Phosphatidylcholine and Deoxycholate. Which indications and what to expect

In the context of the Institute BCN's participation in the 5 Continent Congress in Barcelona, Dr. Sylvie Lederlé will give a talk on lipolysis with PPC and DOC

Institute BCN is participating at 5CC Barcelona from 29th August to 1st September 2019. You will find us at booth #10.

Our collaborator Dr. Sylvie Lederlé will give the lecture “Lipolysis with Phosphatidylcholine and Deoxycholate. Which indications and what to expect” on Friday, August 30 from 9 am within the topic block “My body is my castle”.

Find the abstract below:

Chemical adipolysis: Since the development of liposuction, there have been successive attempts to develop treatments to reduce localized adipose tissue deposits. Lipolysis is a technique of dissolving stored fat, using Phosphatidylcholine (PPC) in association with Deoxycolate (DOC) in order to achieve a sculpting effect by non-surgical means. It can only be of use on small fat deposits.
Mode of action: DOC together with PPC activates lipases inducing membrane breakdown. The released lipid particles are emulsified, dissolved, and transported by high-density lipoproteins (HDL) to the liver.
Indications: Any localization where fat can be pinched between 2 fingers. On the Body mainly abdominal fat, but also hips, innner thigh, knees, inner arms, lower part of the buttocks… On the face mainly double chin, but also lower part of the cheeks and face contour…
Treatment modalities: Injections must be performed in the fat layer, below 5 mm and up to 15 mm below the skin, depending on the thickness of the fat deposit. A grid pattern from 1- to 1.5-cm between the injection points is recommended. PPC acts over the course of more than 8 weeks, which means that there should be a two-month interval between sessions on the same area.
Post-Operative Outcome: Edema, along with mild pain and redness, lasting from 1-4 days and bruises are common. Paresthesia, small temporary nodules, and site infections have been reported.
Side Effects: Cases of necrosis have been seen due to injections being performed too superficially. With higher quantities than recommended, nausea, diarrhea, light-headedness, and headaches have been reported. No signs of inflammation, or any change has been detected in blood work post treatment, such as increased glycemia, cholesterol, or lipid values.
CONCLUSION: Lipolysis associating PPC and DOC is a very efficient treatment for small fat deposits with very moderate side effects. Good complimentary method to liposuction or cryolipolysis.

  • Check all the congress information in the 5CC Newsletter
  • Download the full conference program here

We look forward to see you soon in Barcelona!

Photo by Aleksandar Pasaric from Pexels

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